Ağrı kesici ilaçların fazla kullanımı böbrek rahatsızlıklarına neden olabiliyor

Trakya Üniversitesi Sağlık Bilimleri Fakültesi Dekanı Prof. Dr. Sedat Üstündağ, ağrı kesici ilaçların aşırı kullanımının böbrek yapısını bozarak böbrek yetersizliğine neden olduğunu söyledi.

Trakya Üniversitesi Sağlık Bilimleri Fakültesi Dekanı Prof. Dr. Sedat Üstündağ,  AA muhabirine, diyaliz tedavisi ya da nakil olmazsa hayatını kaybetme riski bulunan hasta sayısının Türkiye'de her geçen gün arttığını ifade etti.

Böbrek yetersizliğinin dünya genelinde en çok artan ülkelerden birinin Türkiye olduğuna dikkat çeken Üstündağ, "1990'lı yılların sonunda Türkiye'de son dönem böbrek hastası, yani diyaliz veya nakil olmazsa yaşamayacak durumda olan hastaların sayısı 1 milyonda yaklaşık 300-350 kişiydi. Günümüzde son rakamalar 1 milyonda 1000 civarında. 20 yıllık dönemde Türkiye'de son dönem böbrek hastalığı, nakil ve diyaliz olmazsa yaşamını sürdüremeyecek hastaların oranı 3 kat artmış oldu." dedi.

Üstündağ, böbrek hastalığının ölüme yol açma konusunda pek çok kanser türünden daha ağır sonuçlar doğurduğunu, böbrek yetersizliğinin birçok sebebinin bulunduğunu belirtti.

Yaşam kalitesini bozan önemli hastalıklar için risk faktörü olan obezitenin böbrek hastalığının gelişiminde önemli bir etken olduğuna değinen Üstündağ, "Kilo fazlalığı tek başına böbreği bozucu bir faktördür. Hareketsiz yaşamın artışı ve işlenmiş hazır gıdalarla beslenmenin artışı obeziteyi beraberinde getiriyor." diye konuştu.

"Ağrı kesiciler böbreği olumsuz etkiliyor"

Prof. Dr. Üstündağ, ağrı kesicilerin birçoğunun da böbreği olumsuz etkilediğini, kadınların daha sık ağrı kesici kullandığına dikkat çekti.

Ağrı kesicilerin bilinçsiz ve kontrolsüz şekilde tüketildiğini ve durumun hastalarda böbrek yetersizliğinin gelişmesine neden olduğunu aktaran Üstündağ, şunları kaydetti:

Ağrı kesicilerin pek çoğu böbreğe dokunuyor. Ağrı kesicilerin fazla kullanılması böbrek yapısını bozuyor. Bir insan hayatı boyunca bir kilogram ağrı kesici tüketirse onun böbrekleri muhakkak belli bir derecede bozulur. Eğer 2-3 kilogram ağrı kesici ilaç tüketirse, bu hastalarda son dönem böbrek hastalığı görmek mümkün olur. Bu hastalar yaşama tutunmak için nakil veya diyaliz tedavisi görmek zorunda kalır. Ortalama bir ağrı kesicinin yarım gram olduğunu düşünürsek, günde bir tane kullanıldığında yılda yaklaşık 200 gram kullanılmış oluyor. Kullanmaya devam edildiğinde 5 sene sonra muhakkak böbreğinizi bozmuş oluyorsunuz. Bizim ülkemizde komşu tavsiyesiyle, arkadaş önerisiyle ağrı kesici kullanımları böbrek hastalığının çok önemli nedeni. Örneğin bir hastanın hipertansiyon nedeniyle enseden başlayıp omuzlara yayılan ağrısı var, bu hastalık tedavi edileceğine ağrı kesici kullanılırsa böbrekler zarar görüyor. Kemik ağrıları olan bir kişi bu hastalığı tedavi etmek yerine ağrı kesici kullanırsa, var olan hastalığın üzerine yeni bir hastalık eklemiş oluyor."

Üstündağ, böbrek nefronlarının gelişiminin anne karnında tamamlandığını, doğumdan sonra böbreklerde yeni bir nefron üremediğini, anne ve çocuk açısından hayati tehlike olmadığı halde zamanından erken yapılan sezaryen doğumların, bebeklerin böbrek gelişimini etkilediğini, bu durumun ileriki yaşlarda böbrek yetersizliğine neden olabildiğini de sözlerine ekledi.

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Adrianphery (doğrulanmamış) Sa, 05/08/2025 - 23:23

While manufacturers continue to tweak their products to overcome the stigma of ultraprocessed foods, nutritionists suggest consumers move forward in choosing products that help the planet — as long as they keep reading the nutrition label.

“I would look for something with a good fat composition in which saturated fat is less than a third of the total fat,” Willett said. “Some vegetable burgers made from peas and legumes can be quite starchy, which the body breaks down similarly to sugar, so I would prefer to see alternatives with more healthy fat, more nuts, more soy.”
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While the Dietary Guidelines for Americans call for a limit of 2,300 milligrams of sodium per day for adults, “the American Heart Association recommends a limit of 1,500 milligrams for adults over 50, which is the standard I prefer,” Willett said.

“Look for about 1 milligram of sodium per calorie, which is a pretty good criteria,” he added. “In general, salt and saturated fat are the two really important factors — along with something that’s flavorful or delicious, which is, of course, up to the consumer.”
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One more key point from Willett: Before plant-based meats can truly help save the planet, they need to come down in price.

“These products are quite a bit more expensive, from what I’ve seen, than basic hamburger,” he said, “and we really need products that are price competitive with the beef and pork if we’re going to see them used on a daily basis, not just by people who can afford it.”

Foberthix (doğrulanmamış) Çar, 06/08/2025 - 18:23

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Zacharypinia (doğrulanmamış) Cu, 08/08/2025 - 16:45

Just when we thought the Coldplay Jumbotron controversy had run its course, Gwyneth Paltrow has entered the chat.

The Academy Award-winning actress and Goop founder appeared in a new – and very funny – ad for Astronomer, the tech firm whose former CEO and human resources chief launched a million memes after being shown on a Jumbotron at a Coldplay concert last week.
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“I’ve been hired on a very temporary basis to speak on behalf of the 300-plus employees at Astronomer,” Paltrow said in the clip shared on the company’s Instagram on Friday night, adding that Astronomer had received “a lot of questions over the last few days.”

In addition to her other hats, Paltrow, of course, is also the famously “consciously uncoupled” ex-wife of Coldplay frontman Chris Martin, who at a concert in Boston last week inadvertently revealed an intimate moment between two top executives at Astronomer – who were seen embracing but immediately ducked from view – during a performance of Coldplay’s “Jumbotron Song.”
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“Whoa, look at these two,” Martin quipped at the time. “Either they’re having an affair or they’re just very shy.”

The moment caused a major internet sensation and an immediate spotlight on Astronomer. Both executives shown in the video have since resigned.

In the clip featuring Paltrow on Friday, the “questions” she addresses do not deal with the controversy, but rather the tech-focused business dealings of New York-based firm Astronomer.

The clip’s caption read simply, “Thank you for your interest in Astronomer.”

Albertner (doğrulanmamış) Cu, 08/08/2025 - 21:51

Just when we thought the Coldplay Jumbotron controversy had run its course, Gwyneth Paltrow has entered the chat.

The Academy Award-winning actress and Goop founder appeared in a new – and very funny – ad for Astronomer, the tech firm whose former CEO and human resources chief launched a million memes after being shown on a Jumbotron at a Coldplay concert last week.
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“I’ve been hired on a very temporary basis to speak on behalf of the 300-plus employees at Astronomer,” Paltrow said in the clip shared on the company’s Instagram on Friday night, adding that Astronomer had received “a lot of questions over the last few days.”

In addition to her other hats, Paltrow, of course, is also the famously “consciously uncoupled” ex-wife of Coldplay frontman Chris Martin, who at a concert in Boston last week inadvertently revealed an intimate moment between two top executives at Astronomer – who were seen embracing but immediately ducked from view – during a performance of Coldplay’s “Jumbotron Song.”
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“Whoa, look at these two,” Martin quipped at the time. “Either they’re having an affair or they’re just very shy.”

The moment caused a major internet sensation and an immediate spotlight on Astronomer. Both executives shown in the video have since resigned.

In the clip featuring Paltrow on Friday, the “questions” she addresses do not deal with the controversy, but rather the tech-focused business dealings of New York-based firm Astronomer.

The clip’s caption read simply, “Thank you for your interest in Astronomer.”

Gabrielneasp (doğrulanmamış) Ct, 09/08/2025 - 01:22

Stunning images show Arctic glaciers’ dramatic retreat
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Swedish photographer Christian Aslund is riding a small boat along the coast of Spitsbergen, an island in the Norwegian archipelago of Svalbard. Here, deep into the Arctic Circle and midway between Norway and the north pole, he is investigating the health of the glaciers, by comparing them to what they looked like in archival photos.

He takes a picture, trying to place his boat in the exact position occupied by an explorer who took a similar photograph over 100 years ago. But the difference is striking: in the shot from 1918, the boat is heading towards a massive glacier. In the image Aslund took in 2024, he is heading toward what looks like almost bare land.

The comparison is part of a series that Aslund worked on in collaboration with the Norwegian Polar Institute and Greenpeace, to document the retreat of Svalbard’s glaciers over the last century. He visited the area twice — in 2002 and in 2024 — and picked which sites to photograph based on historical images that he found in the institute’s archives.
“In 2002, the widespread knowledge, or acceptance, of climate change wasn’t as broad as it is now,” Aslund says. He published the first set of photos over 20 years ago to create awareness of how much the glaciers were receding. But to his surprise, he received some comments suggesting that the images had been “Photoshopped,” that the glaciers were just expanding and contracting naturally, or that he had taken the pictures in the summer and compared them to archival shots taken in the winter: “But they are not — if you look at at the archive photos, you see that they don’t have any sea ice and not enough snow on the mountains (for it to be winter). And also, in the winter, it’s permanently dark.”

In the summer of 2024, he decided to return, taking pictures at the exact same locations as before. “I had a feeling that the glaciers would have receded even more,” he says, “and that was confirmed. We wanted to show that these glaciers are not going back and forth. They are constantly being pulled back by a warming climate. It’s a major difference.”

The Arctic has been warming twice as fast as the rest of the world since the year 2000, according to the National Oceanic and Atmospheric Administration, but according to other estimates it has warmed even more — four times faster than the global average since 1979. NASA says summer Arctic sea ice is shrinking by 12.2% per decade due to warming temperatures.

AdrianPeask (doğrulanmamış) Ct, 09/08/2025 - 02:42

<p dir="ltr">Дела Моисеева</p><p dir="ltr">Черный юрист продолжает зарабатывать на вредительстве</p><p>&nbsp;</p><p dir="ltr">Георгий Моисеев &ndash; бывший активист движения в защиту кооператива &laquo;Бест Вей&raquo;, а также координатор программы защиты российских консультантов австрийской инвестиционно-консалтинговой компании Hermes Management в судах от обвинений в неосновательном обогащении. Основатель кооператива Роман Василенко и прежний председатель кооператива Сергей Крючек (скончавшийся от рака 22 марта 2025 года) отказали Моисееву в его амбициях стать одним из руководителей кооператива, и Моисеев перешел на сторону атакующих.</p><p dir="ltr">Моисеев попытался захватить власть в кооперативе силой &ndash; сначала скрыто, а потом открыто. Причем активизация его усилий по захвату власти совпала со снятием ареста с части средств кооператива &ndash; на счетах кооператива 4 млрд рублей.</p><p dir="ltr">Осенью прошлого года Моисеев, еще имея статус координатора активистов кооператива и координатора группы пайщиков-юристов, вдруг собирает с членов кооператива доверенности, объясняя это представлением их интересов в гражданском суде по иску прокуратуры о признании деятельности кооператива опасной. Но в суде он не выступает. Зато обрушивается с критикой на руководство кооператива и требует перевыборов.</p><p dir="ltr">Получив отказ, он проводит &laquo;выборы&raquo; самочинно &ndash; в результате которых голосами нескольких десятков из 15 тыс. пайщиков кооператива якобы избирается новым председателем. Изготавливает поддельную печать, создает фишинговые имейл и телеграм канал, пытается зарегистрировать изменения в ЕГРЮЛ &ndash; на что по инициативе сотен пайщиков получает судебный запрет.</p><p dir="ltr">После этого пытается торпедировать работу кооператива подачей жалоб в надзорные органы и призывами к пайщикам не делать в кооператив возвратные платежи за приобретенную недвижимость.</p><p dir="ltr">В действиях Моисеева сразу несколько статей УК:</p><p dir="ltr">&ndash; самоуправство;</p><p dir="ltr">&ndash; мошенничество;</p><p dir="ltr">&ndash; подделка документов;</p><p dir="ltr">&ndash; незаконное использование персональных данных.</p><p dir="ltr">Пайщики и адвокаты кооператива стремятся привлечь Моисеева к гражданской и уголовной ответственности.</p><p>&nbsp;</p><p dir="ltr">Подробности читайте <a href="https://www.rucriminal.info/ru/material/dela-moiseeva">здесь</a></p><p dir="ltr">&nbsp;</p>
Роман Василенко

Joshuaapaph (doğrulanmamış) Ct, 09/08/2025 - 23:08

Since India’s independence from Britain in 1947, the status of English in India has been deeply political – entwined with questions of identity, power, and national direction.

Today, English is one of several official languages in India, spoken by about 10% of the population. Hindi is the first language for around 44% of citizens, according to the 2011 census.
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But in recent years, Modi’s BJP has placed particular emphasis on promoting Hindi and reducing the use of English in public life.

The prime minister almost never delivers speeches in English, preferring Hindi for national addresses such as his monthly radio program. His administration has encouraged officials to use Hindi on social media and in government correspondence – though, after criticism from non-Hindi-speaking states, clarified that this was intended mainly for the Hindi belt in the north.
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When India hosted world leaders for the 2023 G20 summit in New Delhi, invitations were sent out from “Bharat” – the Sanskrit or Hindi name for the country – instead of “India,” fueling speculation that the government aims to ultimately phase out the country’s English designation altogether.

Modi’s critics have been quick to note his political motives behind these moves.

With its roots in the Rashtriya Swayamsevak Sangh (RSS), a right-wing organization that advocates Hindu hegemony within India, the BJP’s language policies resonate with many in a country where nearly 80% of people are Hindu.

Analysts say the BJP is seeking to capitalize on this demographic by promoting language policies that strengthen its support base in the north.

According to Rita Kothari, an English professor from Ashoka University, the government “is certainly interested in homogenizing the country and making Hindi more widespread.”

But that policy can also backfire – in part because many regions, such as Marathi-speaking Maharashtra in the west – are staunchly proud of their local language.

The violent clashes in the state’s megacity Mumbai earlier this month were sparked by the regional government’s controversial decision to make Hindi a compulsory third language in public primary schools.

Pushback and protest has also been especially strong in the south, where English and regional languages such as Tamil, Telugu, and Kannada are valued as symbols of local identity and autonomy.

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