Ağrı kesici ilaçların fazla kullanımı böbrek rahatsızlıklarına neden olabiliyor

medikritik Pt, 07/11/2022 - 08:08
Trakya Üniversitesi Sağlık Bilimleri Fakültesi Dekanı Prof. Dr. Sedat Üstündağ, ağrı kesici ilaçların aşırı kullanımının böbrek yapısını bozarak böbrek yetersizliğine neden olduğunu söyledi.

Trakya Üniversitesi Sağlık Bilimleri Fakültesi Dekanı Prof. Dr. Sedat Üstündağ,  AA muhabirine, diyaliz tedavisi ya da nakil olmazsa hayatını kaybetme riski bulunan hasta sayısının Türkiye'de her geçen gün arttığını ifade etti.

Böbrek yetersizliğinin dünya genelinde en çok artan ülkelerden birinin Türkiye olduğuna dikkat çeken Üstündağ, "1990'lı yılların sonunda Türkiye'de son dönem böbrek hastası, yani diyaliz veya nakil olmazsa yaşamayacak durumda olan hastaların sayısı 1 milyonda yaklaşık 300-350 kişiydi. Günümüzde son rakamalar 1 milyonda 1000 civarında. 20 yıllık dönemde Türkiye'de son dönem böbrek hastalığı, nakil ve diyaliz olmazsa yaşamını sürdüremeyecek hastaların oranı 3 kat artmış oldu." dedi.

Üstündağ, böbrek hastalığının ölüme yol açma konusunda pek çok kanser türünden daha ağır sonuçlar doğurduğunu, böbrek yetersizliğinin birçok sebebinin bulunduğunu belirtti.

Yaşam kalitesini bozan önemli hastalıklar için risk faktörü olan obezitenin böbrek hastalığının gelişiminde önemli bir etken olduğuna değinen Üstündağ, "Kilo fazlalığı tek başına böbreği bozucu bir faktördür. Hareketsiz yaşamın artışı ve işlenmiş hazır gıdalarla beslenmenin artışı obeziteyi beraberinde getiriyor." diye konuştu.

"Ağrı kesiciler böbreği olumsuz etkiliyor"

Prof. Dr. Üstündağ, ağrı kesicilerin birçoğunun da böbreği olumsuz etkilediğini, kadınların daha sık ağrı kesici kullandığına dikkat çekti.

Ağrı kesicilerin bilinçsiz ve kontrolsüz şekilde tüketildiğini ve durumun hastalarda böbrek yetersizliğinin gelişmesine neden olduğunu aktaran Üstündağ, şunları kaydetti:

Ağrı kesicilerin pek çoğu böbreğe dokunuyor. Ağrı kesicilerin fazla kullanılması böbrek yapısını bozuyor. Bir insan hayatı boyunca bir kilogram ağrı kesici tüketirse onun böbrekleri muhakkak belli bir derecede bozulur. Eğer 2-3 kilogram ağrı kesici ilaç tüketirse, bu hastalarda son dönem böbrek hastalığı görmek mümkün olur. Bu hastalar yaşama tutunmak için nakil veya diyaliz tedavisi görmek zorunda kalır. Ortalama bir ağrı kesicinin yarım gram olduğunu düşünürsek, günde bir tane kullanıldığında yılda yaklaşık 200 gram kullanılmış oluyor. Kullanmaya devam edildiğinde 5 sene sonra muhakkak böbreğinizi bozmuş oluyorsunuz. Bizim ülkemizde komşu tavsiyesiyle, arkadaş önerisiyle ağrı kesici kullanımları böbrek hastalığının çok önemli nedeni. Örneğin bir hastanın hipertansiyon nedeniyle enseden başlayıp omuzlara yayılan ağrısı var, bu hastalık tedavi edileceğine ağrı kesici kullanılırsa böbrekler zarar görüyor. Kemik ağrıları olan bir kişi bu hastalığı tedavi etmek yerine ağrı kesici kullanırsa, var olan hastalığın üzerine yeni bir hastalık eklemiş oluyor."

Üstündağ, böbrek nefronlarının gelişiminin anne karnında tamamlandığını, doğumdan sonra böbreklerde yeni bir nefron üremediğini, anne ve çocuk açısından hayati tehlike olmadığı halde zamanından erken yapılan sezaryen doğumların, bebeklerin böbrek gelişimini etkilediğini, bu durumun ileriki yaşlarda böbrek yetersizliğine neden olabildiğini de sözlerine ekledi.

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RolandClemn (doğrulanmamış) Pt, 19/05/2025 - 02:03

Taylor Swift has been subpoenaed in the case between Blake Lively and Justin Baldoni.

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A spokesperson for Swift on Friday told CNN, “Taylor Swift never set foot on the set of this movie, she was not involved in any casting or creative decisions, she did not score the film, she never saw an edit or made any notes on the film, she did not even see ‘It Ends With Us’ until weeks after its public release, and was traveling around the globe during 2023 and 2024.”

“The connection Taylor had to this film was permitting the use of one song, ‘My Tears Ricochet.’ Given that her involvement was licensing a song for the film, which 19 other artists also did, this document subpoena is designed to use Taylor Swift’s name to draw public interest by creating tabloid clickbait instead of focusing on the facts of the case,” the spokesperson added.

CNN has reached out to representatives for Baldoni for comment.

When reached for comment later on Friday, a spokesperson for Lively said Baldoni and his legal team “continue to turn a case of sexual harassment and retaliation into entertainment for the tabloids.”

RolandClemn (doğrulanmamış) Pt, 19/05/2025 - 02:49

Taylor Swift has been subpoenaed in the case between Blake Lively and Justin Baldoni.

Swift – a longtime friend of Lively’s – was first mentioned in connection to the ongoing legal dispute between Lively and her “It Ends with Us” director and costar when text exchanges were revealed to include the name “Taylor” as part of Baldoni’s $400 million defamation countersuit against Lively and her husband Ryan Reynolds in January.
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A spokesperson for Swift on Friday told CNN, “Taylor Swift never set foot on the set of this movie, she was not involved in any casting or creative decisions, she did not score the film, she never saw an edit or made any notes on the film, she did not even see ‘It Ends With Us’ until weeks after its public release, and was traveling around the globe during 2023 and 2024.”

“The connection Taylor had to this film was permitting the use of one song, ‘My Tears Ricochet.’ Given that her involvement was licensing a song for the film, which 19 other artists also did, this document subpoena is designed to use Taylor Swift’s name to draw public interest by creating tabloid clickbait instead of focusing on the facts of the case,” the spokesperson added.

CNN has reached out to representatives for Baldoni for comment.

When reached for comment later on Friday, a spokesperson for Lively said Baldoni and his legal team “continue to turn a case of sexual harassment and retaliation into entertainment for the tabloids.”

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Peterbal (doğrulanmamış) Pt, 19/05/2025 - 18:04

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WilliamHic (doğrulanmamış) Pt, 19/05/2025 - 21:48

Analise Completa do Sweet Bonanza 1000
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No Sweet Bonanza 1000, o tradicional sistema de cascata (cascading reels) e mantido e aprimorado. Cada combinacao vencedora faz com que os simbolos se decomponham e novos simbolos caiam, criando a chance de multiplas vitorias numa unica rodada. Diferencial Principal:

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EugeneTut (doğrulanmamış) Pt, 19/05/2025 - 23:23

It wasn’t the most contentious meeting the Oval Office has ever seen. Nor was it the warmest.
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Instead, the highly anticipated meeting Tuesday between President Donald Trump and his new Canadian counterpart Mark Carney fell somewhere in the middle: neither openly hostile nor outwardly chummy, evincing very little neighborliness, at least the type used on neighbors one likes.
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The midday talks illustrated neatly the new dynamic between the once-friendly nations, whose 5,525-mile border — the world’s longest — once guaranteed a degree of cooperation but which, to Trump, represents something very different.
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“Somebody drew that line many years ago with, like, a ruler, just a straight line right across the top of the country,” Trump said in the Oval Office as his meeting was getting underway. “When you look at that beautiful formation when it’s together – I’m a very artistic person, but when I looked at that, I said: ‘That’s the way it was meant to be.’”

That is not how Carney believes it was meant to be.

“I’m glad that you couldn’t tell what was going through my mind,” Carney told reporters later that day about the moment Trump made that remark.
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Still, Carney didn’t entirely hold his tongue.

In a meeting dominated by Trump’s comments — he spoke 95% of the time on all manner of topics, from the Middle East to Barack Obama’s presidential library to the state of high-speed rail in California — it was the new prime minister’s pushback on the president’s ambition to make Canada the 51st US state that stood out.

“As you know from real estate, there are some places that are never for sale,” he said, drawing a begrudging “that’s true” from Trump before Carney carried on.
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PhilipAntig (doğrulanmamış) Cu, 23/05/2025 - 02:23

Всё о строительстве домов из газобетона: проекты, цены и особенности
Строительство домов из газобетона становится всё более популярным благодаря своим преимуществам: энергоэффективности, экологичности и быстроте возведения. Ниже вы найдете подробную информацию о различных аспектах этого материала и услугах, связанных с его использованием.
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Почему выбирают газобетон для строительства дома?
Газобетон — это легкий ячеистый бетон, обладающий отличными теплоизоляционными свойствами, высокой прочностью и экологической безопасностью. Он идеально подходит для возведения как одноэтажных, так и двухэтажных домов, а также для реализации различных архитектурных проектов.

Виды домов из газобетона
Одноэтажные дома из газобетона
Проекты одноэтажных домов из газобетона — оптимальный выбор для тех, кто ценит комфорт и простоту.
Дом из газобетона под ключ — включает все этапы строительства и отделки.
Цена дома из газобетона под ключ в Москве и Московской области — зависит от площади, проекта и выбранных материалов.
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Проекты двухэтажных домов из газобетона — позволяют реализовать просторные жилые пространства.
Строительство домов из газобетона — быстрое и экономичное решение.
Строительство под ключ: этапы и особенности
Фундамент для дома из газобетона — ленточный фундамент является наиболее популярным и надежным.
Строительство из газобетона — включает возведение стен, утепление, отделочные работы.
Стоимость строительства дома из газобетона под ключ — зависит от площади, сложности проекта и региона.
Цены на строительство под ключ
В Москве и Московской области — от 25 000 до 45 000 руб. за м?.
В других регионах — цены могут быть ниже.
Почему стоит заказать строительство дома из газобетона под ключ?
Экономия времени и сил — все этапы от проектирования до отделки выполняются профессионалами.
Гарантия качества — использование проверенных технологий и материалов.
Возможность выбрать готовый проект или заказать индивидуальный дизайн.
Можно ли построить дом из газобетона своими руками?
Теоретически — да, при наличии строительных навыков и опыта. Однако для обеспечения надежности и соответствия строительных норм рекомендуется доверить работу профессионалам.

ArchieFew (doğrulanmamış) Cu, 23/05/2025 - 19:25

Грузоперевозки: Надежное решение для бизнеса и частных клиентов
Грузоперевозки — это важная составляющая современной логистики, обеспечивающая доставку товаров и грузов по Москве, России и за её пределами. В условиях динамичного рынка и растущих требований к скорости и безопасности перевозок, транспортные компании предлагают широкий спектр услуг, адаптированных под любые нужды клиентов.
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Особое значение имеет грузоперевозки по Москве и Московской области. Здесь востребованы как небольшие перевозки, так и крупные, например, перевозка станков или негабаритных грузов. Для этого используют различные виды транспорта, включая трал — низкорамный трал, предназначенный для перевозки спецтехники и крупногабаритных грузов. Трал — это надежное решение для транспортировки тяжелых и габаритных грузов, таких как трансформаторы или строительная техника.

Междугородние грузоперевозки по России
Грузоперевозки по России требуют особого подхода, поскольку страна обладает огромной территорией и разнообразными климатическими условиями. Транспортные компании предлагают услуги по перевозке грузов на любые расстояния, включая междугородние перевозки и доставку грузов из Москвы по всей России. Особенно популярны услуги по перевозке грузов до 20 тонн, что идеально подходит для малого и среднего бизнеса.

Виды грузовых перевозок и транспортные средства
Для различных типов грузов используются разные виды транспорта:

Автомобильные грузоперевозки — наиболее распространенный вид, подходит для перевозки грузов по Москве и России.
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Перевозка опасных грузов — с соблюдением всех требований безопасности.
Недорогие грузоперевозки и доставка
Многие клиенты ищут грузоперевозки по Москве и области недорого. Сегодня существует множество транспортных компаний, предлагающих услуги по разумным ценам, сохраняя при этом высокий уровень сервиса. Заказать грузовую машину или услугу по перевозке можно через онлайн-заявки, что значительно упрощает процесс.

Особенности и преимущества
Доставка грузов по Москве и области — быстро и надежно.
Перевозка негабаритных и габаритных грузов — с использованием специальных тралов.
Перевозка станков и оборудования — с учетом всех требований безопасности.
Транспортные компании по России — обеспечивают доставку в любой регион страны.
Перевозки по России недорого — благодаря оптимизации маршрутов и автопарка.

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