Ağrı kesici ilaçların fazla kullanımı böbrek rahatsızlıklarına neden olabiliyor

medikritik Pt, 07/11/2022 - 08:08
Trakya Üniversitesi Sağlık Bilimleri Fakültesi Dekanı Prof. Dr. Sedat Üstündağ, ağrı kesici ilaçların aşırı kullanımının böbrek yapısını bozarak böbrek yetersizliğine neden olduğunu söyledi.

Trakya Üniversitesi Sağlık Bilimleri Fakültesi Dekanı Prof. Dr. Sedat Üstündağ,  AA muhabirine, diyaliz tedavisi ya da nakil olmazsa hayatını kaybetme riski bulunan hasta sayısının Türkiye'de her geçen gün arttığını ifade etti.

Böbrek yetersizliğinin dünya genelinde en çok artan ülkelerden birinin Türkiye olduğuna dikkat çeken Üstündağ, "1990'lı yılların sonunda Türkiye'de son dönem böbrek hastası, yani diyaliz veya nakil olmazsa yaşamayacak durumda olan hastaların sayısı 1 milyonda yaklaşık 300-350 kişiydi. Günümüzde son rakamalar 1 milyonda 1000 civarında. 20 yıllık dönemde Türkiye'de son dönem böbrek hastalığı, nakil ve diyaliz olmazsa yaşamını sürdüremeyecek hastaların oranı 3 kat artmış oldu." dedi.

Üstündağ, böbrek hastalığının ölüme yol açma konusunda pek çok kanser türünden daha ağır sonuçlar doğurduğunu, böbrek yetersizliğinin birçok sebebinin bulunduğunu belirtti.

Yaşam kalitesini bozan önemli hastalıklar için risk faktörü olan obezitenin böbrek hastalığının gelişiminde önemli bir etken olduğuna değinen Üstündağ, "Kilo fazlalığı tek başına böbreği bozucu bir faktördür. Hareketsiz yaşamın artışı ve işlenmiş hazır gıdalarla beslenmenin artışı obeziteyi beraberinde getiriyor." diye konuştu.

"Ağrı kesiciler böbreği olumsuz etkiliyor"

Prof. Dr. Üstündağ, ağrı kesicilerin birçoğunun da böbreği olumsuz etkilediğini, kadınların daha sık ağrı kesici kullandığına dikkat çekti.

Ağrı kesicilerin bilinçsiz ve kontrolsüz şekilde tüketildiğini ve durumun hastalarda böbrek yetersizliğinin gelişmesine neden olduğunu aktaran Üstündağ, şunları kaydetti:

Ağrı kesicilerin pek çoğu böbreğe dokunuyor. Ağrı kesicilerin fazla kullanılması böbrek yapısını bozuyor. Bir insan hayatı boyunca bir kilogram ağrı kesici tüketirse onun böbrekleri muhakkak belli bir derecede bozulur. Eğer 2-3 kilogram ağrı kesici ilaç tüketirse, bu hastalarda son dönem böbrek hastalığı görmek mümkün olur. Bu hastalar yaşama tutunmak için nakil veya diyaliz tedavisi görmek zorunda kalır. Ortalama bir ağrı kesicinin yarım gram olduğunu düşünürsek, günde bir tane kullanıldığında yılda yaklaşık 200 gram kullanılmış oluyor. Kullanmaya devam edildiğinde 5 sene sonra muhakkak böbreğinizi bozmuş oluyorsunuz. Bizim ülkemizde komşu tavsiyesiyle, arkadaş önerisiyle ağrı kesici kullanımları böbrek hastalığının çok önemli nedeni. Örneğin bir hastanın hipertansiyon nedeniyle enseden başlayıp omuzlara yayılan ağrısı var, bu hastalık tedavi edileceğine ağrı kesici kullanılırsa böbrekler zarar görüyor. Kemik ağrıları olan bir kişi bu hastalığı tedavi etmek yerine ağrı kesici kullanırsa, var olan hastalığın üzerine yeni bir hastalık eklemiş oluyor."

Üstündağ, böbrek nefronlarının gelişiminin anne karnında tamamlandığını, doğumdan sonra böbreklerde yeni bir nefron üremediğini, anne ve çocuk açısından hayati tehlike olmadığı halde zamanından erken yapılan sezaryen doğumların, bebeklerin böbrek gelişimini etkilediğini, bu durumun ileriki yaşlarda böbrek yetersizliğine neden olabildiğini de sözlerine ekledi.

Yorumlar

ArchieFew (doğrulanmamış) Sa, 27/05/2025 - 17:24

Грузоперевозки: Надежное решение для бизнеса и частных клиентов
Грузоперевозки — это важная составляющая современной логистики, обеспечивающая доставку товаров и грузов по Москве, России и за её пределами. В условиях динамичного рынка и растущих требований к скорости и безопасности перевозок, транспортные компании предлагают широкий спектр услуг, адаптированных под любые нужды клиентов.
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Грузоперевозки по Москве и области
Особое значение имеет грузоперевозки по Москве и Московской области. Здесь востребованы как небольшие перевозки, так и крупные, например, перевозка станков или негабаритных грузов. Для этого используют различные виды транспорта, включая трал — низкорамный трал, предназначенный для перевозки спецтехники и крупногабаритных грузов. Трал — это надежное решение для транспортировки тяжелых и габаритных грузов, таких как трансформаторы или строительная техника.

Междугородние грузоперевозки по России
Грузоперевозки по России требуют особого подхода, поскольку страна обладает огромной территорией и разнообразными климатическими условиями. Транспортные компании предлагают услуги по перевозке грузов на любые расстояния, включая междугородние перевозки и доставку грузов из Москвы по всей России. Особенно популярны услуги по перевозке грузов до 20 тонн, что идеально подходит для малого и среднего бизнеса.

Виды грузовых перевозок и транспортные средства
Для различных типов грузов используются разные виды транспорта:

Автомобильные грузоперевозки — наиболее распространенный вид, подходит для перевозки грузов по Москве и России.
Рефрижераторные перевозки — для перевозки скоропортящихся продуктов.
Низкорамные тралы — для тяжелых и негабаритных грузов.
Перевозка опасных грузов — с соблюдением всех требований безопасности.
Недорогие грузоперевозки и доставка
Многие клиенты ищут грузоперевозки по Москве и области недорого. Сегодня существует множество транспортных компаний, предлагающих услуги по разумным ценам, сохраняя при этом высокий уровень сервиса. Заказать грузовую машину или услугу по перевозке можно через онлайн-заявки, что значительно упрощает процесс.

Особенности и преимущества
Доставка грузов по Москве и области — быстро и надежно.
Перевозка негабаритных и габаритных грузов — с использованием специальных тралов.
Перевозка станков и оборудования — с учетом всех требований безопасности.
Транспортные компании по России — обеспечивают доставку в любой регион страны.
Перевозки по России недорого — благодаря оптимизации маршрутов и автопарка.

RichardJon (doğrulanmamış) Per, 29/05/2025 - 16:39

The American ‘revenge travel’ surge is over. Fear and uncertainty are big factors
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Francisco Ayala and his wife have canceled the cruise they planned to take to see the Northern Lights this year. The reasons are complicated.

Ayala is a natural-born US citizen, and his wife is a naturalized citizen. But given reports of people — even with legal status — being detained and questioned at US borders, Ayala said taking a trip out of the country for fun doesn’t seem worth the potential risk.

Ayala also sees another problem: the economy. “The writing is on the wall … The moment I saw the market volatility, I’m like, ‘Yep, this is not going to be good.’”

Travel advisers are seeing the impact of that uncertainty. More than 80% of the 460 advisers surveyed recently by TravelAge West were “very” or “somewhat” concerned about the impact of a possible economic downturn on their business, and more than half were “very” concerned about the impact of government policies.

Their clients’ top concern was economic uncertainty, followed by worries about the treatment of Americans abroad, safety and security, fears of cost increases due to tariffs, immigration and border policies, and travel restrictions.

“You can’t just take one angle and say, ‘Oh, the economy is having an issue. So let’s find something less expensive,’” said Beci Mahnken, CEO of MEI-Travel. Other clients say, “‘I don’t want to travel to the United States,’ or ‘I don’t want to travel outside the United States.’ … It’s like a rock tunnel, going and going.”

One shaft of light at the end of that tunnel could be savings on last-minute summer trips as travelers increasingly take a wait-and-see stance with their plans.

Hitting a ‘brick wall’
Mahnken first saw signs of trouble in early April, when US stocks plunged over fears of a chaotic trade war.

Mahnken and her travel agency staff started getting phone calls from clients, calling to cancel vacations they had booked or seeking refundable trips. She said they were fearful because their 401(k)s and other investments had taken a dive. That uncertainty, she says, made them pause on discretionary spending like a summer trip.
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Until that moment, Mahnken said, the frenzy of heightened “revenge travel” activity that started after pandemic restrictions lifted had not slowed over the course of four years.

“We were still on this incredible high,” Mahnken said. “And then … it almost hit a brick wall.”
Flight analytics firm Cirium pulled flight booking data from online travel agencies from the end of January through early May, when people typically book summer trips. That data, which Cirium shared with CNN, indicates that bookings for travel in June, July and August are down nearly 10% when looking at flights from major US airports to favorite European destinations, compared to the same period last year.

Flights booked in the opposite direction from Europe to the US are down 12% in the same period. That substantial drop is unusual, according to Jeremy Bowen, CEO of Cirium.

“We don’t often see it as wholesale as this and over such a short period of time. Really, that Q1 booking is really quite substantially lower since the beginning of the year,” said Bowen.

Brycesleda (doğrulanmamış) Ct, 31/05/2025 - 04:11

Orbiter Finance: Connecting DeFi Ecosystems
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At its core, Orbiter Finance provides a comprehensive ecosystem designed to facilitate cross-chain interactions, liquidity pooling, and decentralized trading. Its primary goal is to enable users to move assets effortlessly between different blockchain networks, ensuring liquidity and accessibility.

Orbiter Swap
Orbiter Swap is a decentralized exchange (DEX) protocol within the Orbiter ecosystem. It allows users to swap tokens across various blockchains with minimal friction, leveraging the platform’s interoperability features. Orbiter Swap emphasizes low slippage, high security, and fast transaction times.

Orbiter Fi
Orbiter Fi is the yield farming and liquidity provision platform of Orbiter Finance. It enables users to stake their tokens, earn rewards, and participate in liquidity pools across multiple chains. Orbiter Fi aims to maximize returns while maintaining cross-chain compatibility.

Orbiter Bridge
Orbiter Bridge is a core component that facilitates cross-chain asset transfers. It acts as a bridge protocol, securely moving tokens and data between different blockchain networks. The Orbiter Bridge ensures interoperability, security, and speed for cross-chain transactions.

Orbiter Finance Bridge
Orbiter Finance Bridge specifically refers to the bridge infrastructure within the Orbiter ecosystem that connects various blockchain networks. It supports seamless transfer of assets, such as tokens and stablecoins, enabling users to leverage DeFi opportunities across multiple chains.

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Orbiter Bridge Finance encompasses the entire cross-chain transfer and interoperability infrastructure provided by Orbiter. It integrates with Orbiter Swap and Orbiter Fi to create a unified DeFi experience, allowing users to access liquidity, earn yields, and swap tokens across different blockchain ecosystems efficiently.

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Stargate Finance Overview
Stargate Finance provides a unified platform that enables users to transfer assets across different blockchains efficiently and securely. By leveraging its Stargate Bridge and Stargate Swap functionalities, the protocol ensures high liquidity, low slippage, and fast transaction speeds, making cross-chain DeFi more accessible.

Stargate Finance Bridge
The Stargate Bridge is a core component that facilitates cross-chain asset transfers. It allows users to move tokens from one blockchain to another without the need for multiple steps or intermediaries. The bridge is designed for security, speed, and minimal slippage, supporting a wide range of assets.

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Orbiter Finance: Connecting DeFi Ecosystems
Orbiter Finance is a cutting-edge decentralized finance (DeFi) platform focused on interoperability, liquidity, and seamless asset transfer across multiple blockchains. Its suite of tools and protocols, including Orbiter Swap, Orbiter Fi, and Orbiter Bridge, aims to enhance user experience and expand DeFi capabilities.
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Orbiter Finance Overview
At its core, Orbiter Finance provides a comprehensive ecosystem designed to facilitate cross-chain interactions, liquidity pooling, and decentralized trading. Its primary goal is to enable users to move assets effortlessly between different blockchain networks, ensuring liquidity and accessibility.

Orbiter Swap
Orbiter Swap is a decentralized exchange (DEX) protocol within the Orbiter ecosystem. It allows users to swap tokens across various blockchains with minimal friction, leveraging the platform’s interoperability features. Orbiter Swap emphasizes low slippage, high security, and fast transaction times.

Orbiter Fi
Orbiter Fi is the yield farming and liquidity provision platform of Orbiter Finance. It enables users to stake their tokens, earn rewards, and participate in liquidity pools across multiple chains. Orbiter Fi aims to maximize returns while maintaining cross-chain compatibility.

Orbiter Bridge
Orbiter Bridge is a core component that facilitates cross-chain asset transfers. It acts as a bridge protocol, securely moving tokens and data between different blockchain networks. The Orbiter Bridge ensures interoperability, security, and speed for cross-chain transactions.

Orbiter Finance Bridge
Orbiter Finance Bridge specifically refers to the bridge infrastructure within the Orbiter ecosystem that connects various blockchain networks. It supports seamless transfer of assets, such as tokens and stablecoins, enabling users to leverage DeFi opportunities across multiple chains.

Orbiter Bridge Finance
Orbiter Bridge Finance encompasses the entire cross-chain transfer and interoperability infrastructure provided by Orbiter. It integrates with Orbiter Swap and Orbiter Fi to create a unified DeFi experience, allowing users to access liquidity, earn yields, and swap tokens across different blockchain ecosystems efficiently.

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Stargate Finance is a leading protocol in the decentralized finance (DeFi) space, specializing in seamless cross-chain liquidity transfer and asset swapping. Its innovative solutions, including Stargate Bridge, Stargate Swap, and Stargate Crypto Bridge, aim to revolutionize how users interact with multiple blockchain ecosystems.

Stargate Finance Overview
Stargate Finance provides a unified platform that enables users to transfer assets across different blockchains efficiently and securely. By leveraging its Stargate Bridge and Stargate Swap functionalities, the protocol ensures high liquidity, low slippage, and fast transaction speeds, making cross-chain DeFi more accessible.

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The Stargate Bridge is a core component that facilitates cross-chain asset transfers. It allows users to move tokens from one blockchain to another without the need for multiple steps or intermediaries. The bridge is designed for security, speed, and minimal slippage, supporting a wide range of assets.

Stargate Crypto Bridge
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Stargate Swap
Stargate Swap is a decentralized exchange (DEX) feature that allows users to swap tokens directly across different chains. It combines liquidity pools with cross-chain capabilities, enabling efficient and low-cost token swaps without leaving the Stargate ecosystem.

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Aerodrome Finance: Innovations and Opportunities
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Velodrome Finance Swap
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Velodrome Fi
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Velodrome Finance Exchange
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